讲座：
Distributed Cortico-Cortical Interactions Underlying Visual Working Memory
吕海东老师邀请了美国蒙大纳州立大学的Charles M. Gray教授来实验室做报告，欢迎感兴趣的老师同学参加，报告信息如下：
Title: Distributed Cortico-Cortical Interactions Underlying Visual Working Memory
Time: 2016/10/25, 10-11am
Loacation: Imaging Center, 3rd Floor, Large meeting room.
Speaker: Charles M. Gray, professor, Montana State University
Abstract：
Cognitive processes, such as working memory, engage large neuronal populations spanning widespread cortical and subcortical areas. To further understand the
task dependence, and the spectral, temporal and spatial organization of these activity patterns, we designed a large-scale recording system that enables the chronic implantation of 256 independently movable microelectrodes spanning an entire cerebral hemisphere in macaque monkeys. We implanted this system in
two animals and recorded neuronal activity from more than 50 separate cortical areas while the animals performed an object-based, visual delayed match-to-sample
task and a set of control tasks. Analysis of the unit activity revealed a widespread distribution of task dependent and content specific cellular
responses, concentrated in multiple areas of the prefrontal, premotor, posterior parietal and visual cortices. Analysis of the local field potential (LFP)
revealed striking regional variations in the distribution of spectral power and coherence. These signals displayed a mixture of increases and decreases in magnitude during the task. Coherence and phase-locking analyses revealed widespread, task-dependent patterns of correlated activity that varied in
frequency and phase. These studies provide the first analysis of the temporal and spectral patterns of cortical neuronal activity spanning a cerebral hemisphere in macaque monkeys performing a cognitive task.
