讲座：林庆波教授, 台湾阳明大学
15
2014-07
龚高浪老师邀请了台湾阳明大学的林庆波教授来实验室作学术报告，欢迎感兴趣的老师和同学参加。
报告时间：7月17号（周四）上午9点-10点
报告地点：京师大厦9420会议室
报告题目：In-vivo Mapping of Structural Connectivity in the Human Brain
报告摘要：
Knowledge of functional roles of brain areas and associated connections are of critical importance in the understanding of normal brain functions as well as brain abnormalities. The connectivity pattern is formed by structural links of synapses and associated fiber pathways and the underlying causal relationships measured as cross-correlations or coherence. Neural activity, and by extension neural codes, are constrained by connectivity. It is so shallow and clear to understand the links of neuronal connection with brain activity and consequent brain functions.
For decades neuroscientists exhibited little interest in the connections due to the limit of non-invasive technique. With the advent of diffusion MRI, a technique based on the measurement of water molecular diffusion, the architecture of human neuronal bundles can be more thoroughly scrutinized in vivo. The neuronal microstructure as measured by diffusion imaging appears the importance of the connection in the proper transfer of information among brain regions. New studies have shown its close coupling with the cognitive functions, not only behavioral deviation or dysfunction but also personal variation in cognitive performance such as memory performance, language learning and reading ability.
Within the lecture, I will review the development of diffusion MRI techniques including diffusion-weighted image, q-space image, DTI, HARDI, diffusion spectrum image and related post-processing method and tractography. Further applications based on the derived structural connectivity will be discussed as well.
