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  • Are there alternative routes into long-term memory?
    通往大脑长时记忆的新途径

    Guillén Fernández, Ph.D, Professor
    Director of Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, the Netherlands


    Professor Guillén Fernández is director at the Donders Institute for Brain, Cognition and Behavior and head of the Department of Cognitive Neuroscience, at the Radboud University Medical Center. He is an elected fellow of the Royal Netherlands Academy of Sciences and the Academia Europaea. He served as Advanced Investigator of the European Research Council. His area of research is human cognitive neuroscience in which he studies the brain basis of memory, emotion, and their interaction. He applies an interdisciplinary approach integrating cognitive neuroimaging, genetics, pharmacology and diverse clinical disciplines. He is author of more than 280 articles including articles in renowned journals like Nature, Science, Nature Neuroscience, Neuron, Molecular Psychiatry, and PNAS.

    Abstract
    The hippocampus and neighboring structures are regarded essential for long-term memory formation allowing us to remember past experiences and to retrieve acquired knowledge. However, recent evidence cast doubts on this exclusive role. There is initial support for a model in which hippocampal and medial prefrontal contributions to memory formation are dynamically balanced depending on the ease by which new information can be integrated into existing knowledge structures (i.e., schemas). I will present fMRI studies probing schema-related memory formation and retrieval at the level of local activity, multi-voxel activity pattern and network properties. Results suggest that the medial prefrontal cortex links, during schema encoding, consolidation and retrieval, representations in posterior brain areas, potentially forming the brain-basis of knowledge.


    报告时间:2018925日(周二)下午3-5点
    报告地点:北京师范大学 京师学堂第三会议室(地下一层)