学术交流
  • 交流简介
  • 开放课题
  • 讲座信息
  • 会议信息
  • 基于弥散磁共振成像的脑疾病微结构测量

    龚高浪课题组邀请Christian Beaulieu 教授来我实验室做学术报告,欢迎感兴趣的老师和同学参加。具体报告内容如下:

    题目: 基于弥散磁共振成像的脑疾病微结构测量
    Title: Diffusion Tensor Imaging as a Window to Brain Microstructure with Disease
    报告人:Christian Beaulieu 教授
    时间:5月22日(下周一)下午2:00
    地点:京师大厦9420会议室

    报告人简介:Christian Beaulieu博士现为加拿大阿尔伯塔大学生物医学工程系教授、Peter S Allen磁共振成像研究中心主任 (Scientific Director),获Alberta创新科学家、加拿大科研讲席教授等荣誉。Beaulieu教授是国际知名的弥散磁共振影像专家,自1990年开始从事该领域研究,在早期通过不同的神经系统离体模型,系统解析了脑内水分子弥散异向性的微观机制,具有广泛的国际影响,相关综述文章(单作者) google scholar引用已超3000次。现阶段,Beaulieu教授的研究主要集中在弥散磁共振成像新技术的研发与应用,包括脑白质在正常发育、正常老化、以及不同神经精神疾病中(如脑卒中、癫痫、胎儿酒精谱系症、多发硬化等)的变化,目前发表SCI论文百余篇,google scholar总引用14000余次。

    报告摘要: Magnetic resonance imaging (MRI) has made major advances for the non-invasive study of human brain structure in unprecedented ways that has led to improvements in the diagnosis of brain disorders as well as insights for fundamental neuroscience research. At a glance, MRI appears to possess only gross anatomical information at coarse resolution, but the contrast generated is due to the interactions of water (the molecule typically being measured in MRI) with its local tissue micro-environment at the level of the cells. The focus here will be on diffusion MRI which is sensitive to the mobility of water in tissue and can yield quantitative metrics indicative of the underlying microstructure, such as axon health and myelination in white matter tracts of the brain. This talk will provide an overview on the basics of diffusion MRI, its links with tissue micro-structure as revealed by pre-clinical models (many historical) and human studies of epilepsy, and the use of short diffusion times to provide insights into the mechanisms of acute stroke detection.